Products . . .

GYNIPRAL(hexoprenaline sulphate)  
               
                             UTERO-RELAXENT DRUG

PERTERM LABOUR

-Excessive severe 
-irregular Contractions  
-unwanted felling during pregnancy

GYNIPRAL(hexoprenaline sulphate)  

-Highly selective adrenergic B2 receptors stimulant with minimal effect on B1
-itís selectivity is 5:1 in a comparison   with any other tocolytic  drugs as  (ritodrine, salbutamol)

GYNIPRAL
-no untoward effect on heart rat and blood pressure of both maternal and fetus  
GYNIPRAL
NO TACHYCARDIA NO PALPITATION

 

GYNIPRAL(HEXOPRENALINE SULPHATE)

1-rapidly inhibits sever spontaneous irregular contractions induced preterm labor
2-before, during , after  cervical cercolage
3-Increase intrauterine placental circulation to fix the zygote  in (I.V.F)
4-Rapidly prevent utero-contractions where there is acute asphyxia
5-Increase intrauterine placental circulation so correct the pre-existing O2 deficiency  in fetus
6-Used is some cases of Caesarean sections like Uterine torsion and must be followed with antidote

THE ONLY TOCOLYTIC DRUG    
CAN BE USED SAFLY 

IN IV INJCTION WITHOUT TACHYCARDIA to fetus and mother
One ampoules in 10 ml saline \ ringer 
By i.v  injection slowly for 10 min
Contraction stop at once

GYNIPRAL(hexoprenaline sulphate)

-Longer duration of action in comparison with (ritodrin and salbutamol)
-It has 2 catecholamine linked by 6 methylene groups so if one molecule methylated the other still working and the effect too greatly 
This symmetrically in structure give high degree of binding capacity onB2 receptors
-Itís administrations with oral tablet effect after 15 minutes reaching maximum after 2 hours and lasts for 8hours